SPANA for Spectral Data Analyses [Download] Copyright (c) 2010 ykuroda All right reserved.

   SPANA is supplied as the "zip" archive file. Since the file is not a self-extracting archive, the file is necessary to be manually extracted by using an appropriate archive tool.
　After extraction of the archive file, the setup of SPANA starts from double clicking on the "setup.exe" program and following the program's instructions. Since the set up procedure create no icon of SPANA on your desktop, you should make the necessary short cut icon from the "spana.exe" file (usually) in the "c:\Program Files (x86)\spana" folder and place it on an appropriate position. To start SPANA under Windows, double-click on the SPANA icon.
　In the "spana" folder, the simplified manual, sample data for "dat" and "tab" formats, the zip-archive file, "SampleData.zip" containing other sample data, and "ExternalPrograms.zip" containing samples of external programs are included.
For bugs or problems, please inform by e-mail.

Download of SPANA Ver5.5　　　　 　　　*spana55.zip

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Version history
　 * November 5, 2010 : Release Version 5.0.13(beta version) : the number of spectral channels are expanded to be 500.
　 * June 9, 2012 release Version 4.5.14 : Final version of Ver.4
　 * July 20, 2014 release Version 5.1.01 : the function of the access for user's "External program" of the least
　　　　　　　　　　　　　　　　　　　　　　　　　　　 square optimization is added.
　 * June 8, 2015, release Ver.5.3.07 (beta) : the new analysis mode for competitive equilibriums is added
　* May 17, 2018, release Ver.5.4.12 : The model for "One Step 1:n Complex formation" was expanded into that for
　　　　　　　　　　　　　　　　　　　　　　　　　"One Step m:n Complex formation"..
　*May 19, 2019, release Ver. 5.5.9 : Adjust the Window frame to that of Windows 10 as the standard.
　*Aug. 7, 2020, release Ver. 5.5.21 : "Equilibrium Simulation" is added.
　*Aug. 30, 2020, release Ver. 5.5.24 : Minor modifications.
　*Sep. 12. 2020, release Ver. 5.5.27 : Minor bug-fixation for Equilibrium Simulator
　*Sep. 27, 2020, release new version of "External Programs" for SPANA, which contains refined versions of SPANA_LSQ.c and SPANA_REDAP.c 　
　　　　　　　　　　　and sample programs for 64bit WINDOWS
　*Nov. 5, 2020, release Ver. 5.5.42 : Bug-fixation for incompatibilities in drawing of theoretical graph data generated by new External Programs,
　　　　　　　　　　　SPANA_LSQ and SPANA_REDAP.
　*Feb. 4, 2021, release Ver. 5.5.43 : Logistic, Lorentz and Gauss functions were added for the optimization function. + minor modifications.
　*Feb. 9, 2021, release Ver. 5.5.45 : The bug in "Wave Separation" was fixed
　*Nov. 16, 2021, release Ver. 5.5.50 : The functions dealing with the pre-equilibrium of the host molecule were added to the optimization for the
　　　　　　　　　　　sequential 1 : n complex formation model.
　*Nov. 21, 2021, release Ver. 5.5.51 : Minor modification.
　*June 15, 2022, release Ver.5.5.64 : The programs for "Auto- and Manual- Wave Separation" were refined.
　*Dec. 13, 2022, release Ver.5.5.67：The bug in "Linear Lines Generation" (Wave Generation) is fixed..
　*Feb. 13, 2023, release Ver.5.5.70：The model systems, nA <-> A_n (n-Self Aggregation) and A1 <-> A2 (Thermodynamic Analyses) were extended 　　　　　　　　　　　to that of the arbitrary self-reorganization equilibrium, mA <-> nA^*.
　*Mar. 11. 2023, release Ver.5.5.71：The optimization processes for "2nd Order Reacton" are refined.
　*Aug. 5, 2023, release Ver. 5.5.78 : "BEADS"^a), a flat baseline estimation function developed by X. Ning, I. W. Selesnick and L. Duval (Chemometr. Intell. Lab. Syst., Vol. 139, p. 156, 2014), has been added to the "Spectrum-Base Line" menu. A fifth order polynomial has been added to the optimisation function. Minor changes to arithmetic rules between channels with different range widths.
　*Sep. 16, 2023, release Ver. 5.5.79：Minor refinement.
　*July 13. 2024, release Ver. 5.5.85 : Optimization algorithm for "Wave Separation" with the Voigt functions is improved
　*Dec. 6, 2024, release Ver. 5.5.89 : Expansion of SPANA's capacity to read external data (*.lsq file) and enhancement of nonlinear least-square optimization for user-defined functions using SPANA_LSQ and SPANA_REDAP external programs (manuals for both programs attached)
　*Mar. 25, 2025, release Ver. 5.5.91 : Modified Nelder-Mead Simplex optimization algorithm* for the parameter search was added.^b)
　*April 12, 2025, release Ver. 5.5.92 : Operation algorithms for the least square optimization are refined

　a) See the program published at https://github.com/tvijverb/BEADS_Baseline_correction for the BEADS calculation algorithm. Also see https://qiita.com/skotaro/items/d943bc9a50da9410e9cb for an example of its use.
　b) J. A. Nelder, R. Mead, Computer Journal, 7, 308 (1965)
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The general non-linear least square program, LSPE, and the least square program for the reaction kinetics analyses, REDAP, are newly released. These programs are written in C language and run on the DOS box of WINDOWS.
LSPE allows nonlinear least-squares optimization calculations for data with multiple dependent variables, including multiple independent variables
For details, contact by e-mail (yasuhisa.krd@hotmail.co.jp)

　*Mar. 1, 2024, release improved LSPE

Download LSPE　　* lspe.zip
Download REDAP　* redap.zip

(Although SPANA, LSPE and REDAP are the free softwares, the copyright of the programs belongs to Y. Kuroda.)